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House orders blood tests, then tells Wilson he follows his cases and that Tucker’s low white blood cell count and right arm paralysis means his leukemia has returned. House and his team are doing an ultrasound on another patient with stomach pains. Wilson goes to brag to House about his diagnosis, saying he had a "House moment". He is about to call House, but notices the girlfriend has a cold sore which could have caused transverse myelitis in Tucker. Wilson quickly rules out a stroke and the blood tests don't indicate that the cancer has returned. Wilson gets Tucker to the hospital where he meets Tucker's new girlfriend (who he mistakes for his daughter). Tucker thinks he might be having a stroke but Wilson has no idea what is wrong with him.
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He walks over to Tucker who has collapsed on the ground, and Tucker apologizes because he cannot move his arm which is why he blindly fired the shot and almost took Wilson’s head off. As they turn to go to "miss more wild turkeys", a shot rings out that narrowly misses Wilson. Tucker once again thanks Wilson for saving his life.
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Wilson and Tucker go hunting to celebrate Tucker's fifth year of survival after his cancer diagnosis by shooting at an empty chemotherapy bag pinned to a tree. He doesn’t even know your name.” Wilson reminds him that Jim is a common short form of James and that the trait "self-important jerk" seems to attract him in friends and heads back for extra sleep. House wonders why Wilson isn't up by his usual time and he is obviously obsessed when he learns that Wilson is going hunting with his friend Tucker the "self-important jerk" instead of going to work, to which he says: “The guy calls you Jim. House has retrieved his guitar, along with many of his other belongings, from his apartment. House is strumming on his guitar and singing "Faith" by George Michael. Wilson wakes up wondering where a noise is coming from. Meanwhile, Cuddy seeks advice in her search for real estate. With the help of the team, Wilson works to diagnose the patient more optimistic results, but when things take a turn for the worse, Wilson must address his inability to separate patient from friend and he must put his own life at risk. Wilson accepts even though he is reluctant to believe the cancer has returned. House wagers Wilson that the patient's symptoms are attributed to new cancer cells. When an old friend and former patient of Wilson’s exhibits paralysis in his left arm, Wilson puts himself on the case. Wilson is a 6th season episode of House and the tenth episode of the season, that first aired on November 30, 2009. You just cut that out, you‘d be a pretty decent doctor" - Wilson A hundred bucks." Wilson: " Are you serious?!" House: " Look, friends don‘t diagnose friends with cancer, I get it. In this case, you are those other doctors. House: " I look for zebras because other doctors rule out all the horses.